Search Result
Results for "
<i>Ficus erecta<_i> Thunb. var. <i>beecheyana<_i> (Hook.et Arn.) King
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
2
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-137466
-
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Topoisomerase
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Cancer
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ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etoposide (IC50=120 μM). ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research .
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-
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- HY-120813A
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URB913 (enantiomer)
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Others
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Inflammation/Immunology
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ARN 077 enantiomer (19) is the less active enantiomer of ARN 077, with an IC50 of 3.53 μM for rat NAAA .
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-
-
- HY-157223
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-
-
- HY-115777
-
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ROR
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Neurological Disease
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ARN-6039 is an orally available inverse agonist of RORγ for autoimmune demyelinating disease.
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-
-
- HY-148719
-
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Topoisomerase
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Cancer
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ARN24139(compound 3f) is a topoisomerase II (topoII) inhibitor with the IC50 of 7.3 μM. ARN24139 can inhibit cancer cell proliferation and is well tolerated in vivo .
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-
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- HY-103691A
-
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Autophagy
Apoptosis
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Cancer
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ARN5187 trihydrochloride is a lysosomotropic REV-ERBβ ligand with a dual inhibitory activity toward REV-ERB-mediated transcriptional regulation and autophagy. ARN5187 trihydrochloride shows lysosomotropic potency and cytotoxicity. ARN5187 trihydrochloride induces apoptosis .
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-
-
- HY-103691
-
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Autophagy
Apoptosis
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Cancer
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ARN5187 is a lysosomotropic REV-ERBβ ligand with a dual inhibitory activity toward REV-ERB-mediated transcriptional regulation and autophagy. ARN5187 shows lysosomotropic potency and cytotoxicity. ARN5187 induces apoptosis .
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-
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- HY-115498
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Apoptosis
NO Synthase
Interleukin Related
COX
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Neurological Disease
Inflammation/Immunology
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ARN14494 is a potent and selective serine palmitoyltransferase (SPT) inhibitor, with an IC50 of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis, and anti-inflammation. ARN14494 can be used for Alzheimer’s disease research .
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-
-
- HY-163171
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Chloride Channel
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Neurological Disease
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ARN 11391 is a selective enhancer of inositol triphosphate receptor type 1 (ITPR1). ARN 11391 can be used in the study of spinocerebellar ataxia .
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- HY-16060
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Apalutamide
Maximum Cited Publications
9 Publications Verification
Arn-509
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Androgen Receptor
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Cancer
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Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM .
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-
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- HY-124597
-
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Others
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Inflammation/Immunology
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ARN726 is a potent NAAA (N-acylethanolamine acid amidase) inhibitor with an IC50 of 0.073 µM. ARN726 decreases alcohol self-administration in a dose-dependent manner .
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-
-
- HY-120813
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URB913
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Others
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Inflammation/Immunology
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ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA . ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats .
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- HY-145339
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Others
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Neurological Disease
Inflammation/Immunology
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ARN19702 is a selective, orally active, reversible, and brain-penetrant N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 230 nM for human NAAA. ARN19702 has pain relief effects .
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- HY-110101
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-
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- HY-132882
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Others
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Inflammation/Immunology
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ARN19689 is a potent, selective, orally active and non-covalent inhibitor of N‑Acylethanolamine-Hydrolyzing Acid Amidase (NAAA), with an IC50 of 42 nM. ARN19689 is a promising pharmacological tool to be further investigated in the field of inflammatory conditions .
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-
-
- HY-149464
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Ras
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Cancer
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ARN22089 is a oral active novel class of trisubstituted pyrimidine, blocks the interaction of CDC42 GTPases with specific downstream effectors. ARN22089 blocks tumor growth in BRAF mutant mouse melanoma model .
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-
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- HY-RS06287
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Small Interfering RNA (siRNA)
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Others
|
HOOK1 Human Pre-designed siRNA Set A contains three designed siRNAs for HOOK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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-
HOOK1 Human Pre-designed siRNA Set A
HOOK1 Human Pre-designed siRNA Set A
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- HY-RS06288
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Small Interfering RNA (siRNA)
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Others
|
HOOK2 Human Pre-designed siRNA Set A contains three designed siRNAs for HOOK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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-
HOOK2 Human Pre-designed siRNA Set A
HOOK2 Human Pre-designed siRNA Set A
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- HY-RS06289
-
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Small Interfering RNA (siRNA)
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Others
|
HOOK3 Human Pre-designed siRNA Set A contains three designed siRNAs for HOOK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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-
HOOK3 Human Pre-designed siRNA Set A
HOOK3 Human Pre-designed siRNA Set A
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- HY-150514
-
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Others
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Infection
|
ARN1468 (compound 5) is an orally active and potent serpins inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 μM .
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-
-
- HY-120856
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-
-
- HY-12864
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Arn-810; GDC-0810
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Estrogen Receptor/ERR
|
Cancer
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Brilanestrant (ARN-810; GDC-0810) is an orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM.
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-
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- HY-124927
-
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Others
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Cancer
|
ARN14988 is a potent inhibitor of acid ceramidase (ACDase) (IC50=12.8 nM for the human enzyme) .
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- HY-N3895
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Malloprenol-11
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Others
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Others
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Ficaprenol-11 is a compound that can be isolated from the leaves of Ficus elastica .
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- HY-18292
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Amyloid-β
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Neurological Disease
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ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ.
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-
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- HY-103592
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Ceramidase
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Cancer
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ARN14974, a benzoxazolone carboxamide, is a potent and systemically active inhibitors of intracellular acid ceramidase (IC50=79 nM) .
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-
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- HY-118994
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Phospholipase
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Neurological Disease
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ARN19874 is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor with an IC50 of ~34 μM .
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- HY-N3896
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Others
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Others
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Ficusin A is an isoprenylated flavonoid. Ficusin A can be isolated from the twigs of Ficus hispida .
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- HY-144290
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GSK-3
DYRK
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Neurological Disease
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ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation .
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- HY-N11823
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-
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- HY-16060S1
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Arn-509-d3
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Androgen Receptor
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Cancer
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Apalutamide-d3 is the deuterium labeled Apalutamide[1]. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[2].
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- HY-N12575
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Others
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Others
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Physcion-8-O-(6'-O-malonyl)-glucoside can be extracted from the root tuber of Polygonum multiflorum Thunb .
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- HY-N5037
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Others
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Cardiovascular Disease
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Ilexoside D is isolated from the roots of Ilex pubescens Hook. et Arn. Ilexoside D has the anti-tissue factor activity as well as the antithrombotic activity .
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- HY-N7158
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Others
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Cancer
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Elasticamide is a natural compound isolated from Ficus elastica Roxb. Elasticamide inhibits the cell growth in the U373n, with the IC50 of 88 μM .
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-
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- HY-N3857
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Others
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Others
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Erythrinin C is an isoflavones that can be isolated from Erythrina suberosa var .
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- HY-N7359
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Others
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Cancer
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Securitinine is a Securinega alkaloid. Securitinine can be derived from the wood of Japanese medicinal plant Securinega suffruticosa var .
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- HY-16060S2
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Arn-509-13C,d3
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Isotope-Labeled Compounds
Androgen Receptor
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Cancer
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Apalutamide- 13C,d3 is the 13C- and deuterium labeled Apalutamide. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].
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- HY-N10600
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Antibiotic
Bacterial
Fungal
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Infection
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3β-Acetoxyurs-12-en-11-one is a ursane triterpenoid with antimicrobial activity, can be isolated from the stem bark of Morus mesozygia and the leaves of Ficus hirta Vahl (Moraceae) .
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- HY-N9540
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Monoamine Oxidase
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Neurological Disease
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Methyl citrate is a Monoamine oxidase B (MAO-B) inhibitor (IC50=0.23 mM). Methyl citrate is isolated from the fruits of Opuntia ficus-indica var. saboten Makino .
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- HY-N3788
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Others
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Inflammation/Immunology
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Dulcioic acid (compound 19) is a product isolated from Tripterygium wilfordii Hook f. Dulcioic acid shows a significant inhibitory effect on cytokine production .
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- HY-18204A
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LCZ696
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Angiotensin Receptor
Neprilysin
Apoptosis
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Cardiovascular Disease
Endocrinology
Cancer
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Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure . Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis .
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- HY-N6256
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Phosphodiesterase (PDE)
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Cardiovascular Disease
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Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively .
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- HY-32736
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NSC 165677; PG 492
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Wnt
β-catenin
Apoptosis
Autophagy
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Inflammation/Immunology
Cancer
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Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .
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- HY-78086
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3-Methylbenzaldehyde
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Endogenous Metabolite
Bacterial
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Infection
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m-Tolualdehyde (3-Methylbenzaldehyde) is a compound that can be isolated from Ficus carica L. and Myosotis arvensis. m-Tolualdehyde has food protective effects. m-Tolualdehyde shows acaricidal activities for Tyrophagus putrescentiae with a LD50 of 1.97 μg/cm 3 .
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- HY-N3790
-
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Others
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Others
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Durantoside I is a natural product, that can be isolated from the stems of Duranta erecta .
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-
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- HY-P4071
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Cathelicidin-OH antimicrobial peptide
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Bacterial
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Infection
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OH-CATH is a natural antimicrobial peptide that can be isolated from the venom and tissue of Ophiophagus hannah (King Cobra) .
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-
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- HY-N4150
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Quercetagetin-7-O-glucoside
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Others
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Inflammation/Immunology
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Quercetagitrin (Quercetagetin-7-O-glucoside), isolated from the flowers of the Marigold (Tagetes erecta), has anti-inflammatory activity .
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-
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- HY-N0403
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Apoptosis
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Inflammation/Immunology
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2,3,4',5-Tetrahydroxystilbene 2-O-β-D-glucoside (TSG) is an active product that can be extracted from Polygonum multiflorum Thunb. TSG has anti-inflammatory, antioxidative, anti-atherosclerotic, anti-apoptotic, and free radical scavenging activities, TSG is also indicated to facilitate long-term potentiation and learning and memory in both normal and pathological conditions .
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- HY-P3028
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Ficin
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Biochemical Assay Reagents
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Others
Metabolic Disease
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Ficain is an enzyme extract composed of several proteases that can be isolated from Ficus hispida L. and the latex of fig (Ficus carica). Ficain has different specificities in different proportions during fruit ripening. Ficain is widely used in protein hydrolysis, food, production of bioactive peptides and antibody fragments .
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-
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- HY-N10406
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Others
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Others
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Triptonoterpene is a natural product that can be isolated from the roots of Tripterygium wilfordii Hook. f. .
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- HY-N8259
-
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Others
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Others
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Obovatol is a biphenyl ether lignan isolated from the leaves of Magnolia obovata Thunb .
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- HY-N11487
-
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Others
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Others
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Regaloside E is a natural product that can be isolated from Lilium longiflorum Thunb. .
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-
- HY-N2815
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Acetylursolic acid; 3-Acetylursolic acid
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Others
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Cancer
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Ursolic acid acetate (Acetylursolic acid), isolated from the aerial roots of Ficus microcarpa, exhibits cytotoxicity against KB cells with IC50 of 8.4 μM .
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- HY-N1703
-
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|
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24-Methylenecycloartanol is a compound that can be isolated from Ficus krishnae. 24-Methylenecycloartanol can be used for the research of diabetes .
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- HY-N2173
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|
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Forsythoside E is a phenylethanoid glycoside isolated from the fruits of forsythia suspense (thunb.) vahl .
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- HY-N3510
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-
- HY-N0228
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-
- HY-N3839
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7-epi-Vogeloside; Nervoside; Epivogeloside
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Others
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Others
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epi-Vogeloside is a secoiridoid glycoside and a iridoid glucoside, which can be isolated from Lonicera japonica Thunb .
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- HY-N11489
-
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Others
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Others
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Regaloside K (Compd 1) is a natural compound that can be isolated from Easter Lily (Lilium longiflorum Thunb.) .
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- HY-N0476
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Regelide; Abruslactone A
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Others
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Inflammation/Immunology
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Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects .
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- HY-N12014
-
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Others
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Others
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Triptotriterpenic acid C is a ursolic-type acid that can be isolated from total glycosides extracted from the root of Tripterygium wilfordii Hook.f. .
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- HY-RS15604
-
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Small Interfering RNA (siRNA)
|
Others
|
VARS1 Human Pre-designed siRNA Set A contains three designed siRNAs for VARS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
VARS1 Human Pre-designed siRNA Set A
VARS1 Human Pre-designed siRNA Set A
- HY-RS15605
-
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Small Interfering RNA (siRNA)
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Others
|
VARS2 Human Pre-designed siRNA Set A contains three designed siRNAs for VARS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
VARS2 Human Pre-designed siRNA Set A
VARS2 Human Pre-designed siRNA Set A
- HY-N4064
-
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Others
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Others
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Hederagenic acid (compound 2) is a kind of triterpenoid saponin. Hederagenic acid can be isolated from the roots of Kalopanax septemlobus (Thunb.) Koidz .
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- HY-N4277
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NSC-698793
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Others
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Cancer
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Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity .
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- HY-N3009
-
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Others
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Cardiovascular Disease
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Secoxyloganin, isolated from Lonicera japonica Thunb, inhibits the blood flow (BF) decrease. Secoxyloganin has allergy-preventive activity .
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- HY-N2019
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-
- HY-136504
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Dianthrone
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Others
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Others
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Bianthrone (Dianthrone) is a natural product that can be isolated from Rheum officinale Baill. Bianthrone is a potential toxic marker of Polygonum multiflorum Thunb .
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- HY-N5042
-
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Others
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Inflammation/Immunology
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Forsythoside I, a caffeoyl phenylethanoid glycoside (CPG) isolated from the fruits of Forsythia suspense (Thunb.) Vahl, may possesses anti-inflammatory activities .
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- HY-N5043
-
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Others
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Inflammation/Immunology
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Forsythoside H, a caffeoyl phenylethanoid glycoside (CPG) isolated from the fruits of Forsythia suspense (Thunb.) Vahl, may possesses anti-inflammatory activities .
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- HY-N0398
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Opioid Receptor
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Neurological Disease
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Sec-O-Glucosylhamaudol is a natural compound extracted from Peucedanum japonicum Thunb, decreases levels of μ-opioid receptor, with analgesic effect .
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- HY-N12212
-
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Others
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Others
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Triptonoterpene Me ether (compound 5) is a rosinane-type diterpenoid compound, which can be isolated from the traditional Chinese medicine Tripterygium wilfordii Hook. f .
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- HY-N2157
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(+)-Pteryxin
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|
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Pteryxin, a coumarin in Peucedanum japonicum Thunb leaves, exerts antiobesity activity . Pteryxin is a potent butyrylcholinesterase (BChE) inhibitor, with an IC50 of 12.96 μg/ml .
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- HY-N2833
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Adrenergic Receptor
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Neurological Disease
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Akuammigine is an alkaloid that can be found in hook-bearing branch of Uncariarhynchophylla. Akuammigine is a is a very weak antagonist at pre- and postsynaptic α-adrenoceptor of the rat vas deferens .
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- HY-147265A
-
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MicroRNA
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Cancer
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Eldocasiran sodium is a micro-ARN-193a-3p analogue, Eldocasiran sodium has anticancer activity, and can be used for cancer research .
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- HY-B0417A
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-
- HY-N7345
-
-
- HY-N0901
-
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Autophagy
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Neurological Disease
Cancer
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Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
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- HY-N0901B
-
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Autophagy
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Neurological Disease
Cancer
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Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
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- HY-N2887
-
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Others
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Cancer
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Araliadiol is a polyacetylenic compound isolated from the leaves of Aralia cordata Thunb. Araliadiol inhibits MCF-7 cells growth with an IC50 value of 6.41 µg/mL .
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- HY-147265
-
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MicroRNA
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Cancer
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Eldocasiran is a micro-ARN-193a-3p analogue, Eldocasiran has anticancer activity. Eldocasiran can be used for cancer research .
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- HY-N11033
-
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Others
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Others
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Spiranthol A is a natural product that can be isolated from Spiranthes sinensis var. amoena .
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- HY-126655
-
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Others
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Others
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Yunnanxane (compound 1) is a taxane diterpenoid that can be found in Taxus chinensis var. .
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-
- HY-121020
-
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Phosphatase
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Neurological Disease
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Arcapillin is a flavonoid that can be isolated from Artemisia capillaris Thunb. Arcapillin has antispasmodic activity. Arcapillin also has moderate PTP1B inhibitory activity .
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- HY-N8136
-
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Others
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Others
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Volvalerenic acid A is a germacrane-type sesquiterpenoid that can be found in the roots of Valeriana officinalis var. latifolia .
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-
- HY-N2870
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Schisanwilsonin N
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Others
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Others
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Angeloylisogomisin O is a compound isolated from the aerial parts of Schisandra propinqua var. propinqua .
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- HY-N3322
-
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Others
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Others
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Maoecrystal B is a diterpenoids compound isolated from the leaves of Isodon eriocalyx var. laxiflora .
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- HY-N1281
-
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Others
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Others
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Sendanolactone is a new tetracyclic triterpenoid from the bark of M. azedarach L. var. japonica Makino .
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- HY-N8883
-
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Others
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Others
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6-Epiphysalin G is isolated from natural
Physalis alkekengi var. francheti. .
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- HY-N12065
-
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Others
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Others
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Parisyunnanoside H is a steroidal saponin isolated from Paris polyphylla Smith var. yunnanensis .
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- HY-N0590
-
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ERK
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Cardiovascular Disease
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Corynoxeine, isolated from the hook of Uncaria rhynchophylla, is a potent ERK1/ERK2 inhibitor of key PDGF-BB-induced vascular smooth muscle cells (VSMCs) proliferation.
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- HY-N7252
-
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Bacterial
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Infection
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Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever .
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- HY-105713
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Bacterial
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Infection
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Sulochrin is a metabolite produced by Aspergillus terreus var. aureus. I. Sulochrin has antimicrobial activities .
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-
- HY-N7882
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Braxin C; Aquilide A
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Others
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Cancer
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Ptaquiloside is a sesquiterpene glycoside isolated from Pteridium aquilinum var.latiusculum and has carcinogenic activity .
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- HY-N11084
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Others
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Others
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Salviaplebeiaside is a phenolic substance can be isolated from the aerial part of Vitex negundo var. cannabifolia .
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- HY-N3150
-
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Others
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Others
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Ohchinin acetate is a limonoid, that can be isolated from the fruit of M. azedarach Linn. var. japonica Makino .
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- HY-N3585
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Others
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Cancer
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Chrysothol can be isolated from the aerial part of Chrysothamnus viscidiflorus var. and has anticancer activity .
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- HY-121691
-
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Others
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Others
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Sugereoside is a bitter diterpene glucoside. Sugereoside can be isolated from leaves of Ilex sugerokii var .
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- HY-N1933
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Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Macleaya cordata (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current .
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- HY-N1432
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Lirioprolioside B is a steroidal glycoside that can be isolated from the underground organs of Liriope spicata var. prolifera .
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Type |
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- HY-P3028
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Ficin
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Biochemical Assay Reagents
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Ficain is an enzyme extract composed of several proteases that can be isolated from Ficus hispida L. and the latex of fig (Ficus carica). Ficain has different specificities in different proportions during fruit ripening. Ficain is widely used in protein hydrolysis, food, production of bioactive peptides and antibody fragments .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P4071
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Cathelicidin-OH antimicrobial peptide
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Bacterial
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Infection
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OH-CATH is a natural antimicrobial peptide that can be isolated from the venom and tissue of Ophiophagus hannah (King Cobra) .
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Free Sample |
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* This product has been "discontinued".
Optimized version of product available:
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-16060S1
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Apalutamide-d3 is the deuterium labeled Apalutamide[1]. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[2].
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- HY-16060S2
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Apalutamide- 13C,d3 is the 13C- and deuterium labeled Apalutamide. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].
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Cat. No. |
Product Name |
Application |
Reactivity |
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- HY-P82137
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H3 K9 HMTase 2; KMT1B; Su(var)3 9 homolog 2; Suv39h2
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WB, IHC-P, IP
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Human, Mouse, Rat |
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- HY-P81441
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HMGA2; HMGIC; High mobility group protein HMGI-C; High mobility group AT-Hook protein 2
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IHC-P
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Human |
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